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For amputees with vascular disease, exercise can scale back signs of PVD similar to breathlessness, angina and intermittent claudication pain usually felt throughout walking. Your pulse fee earlier than and proper after strolling 1 mile (1.6 kilometers). The rise in exercise of synthesis of norepinephrine and epinephrine throughout the medulla is finished from glucocorticoids by the rise in reaction price of sure enzymes, akin to: tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine-β-hydroxylase, and phenylethanolamine N-methyltransferase. When the physique receives sensory information, the sympathetic nervous system sends a sign to preganglionic nerve fibers, which activate the adrenal medulla by acetylcholine. Chromaffin cells contained within the adrenal medulla act as postganglionic nerve fibers that launch this chemical response into the blood as a circulating messenger. The sympathoadrenal system can activate and discharge chemical messengers as a single unit to activate an organism's "fight or flight" response. Electrical impulses carried by the sympathetic nervous system are converted to a chemical response within the adrenal gland.
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