Purpose: The intention of this study was to judge the connection between retinal blood stream (RBF) and retinal blood oxygen saturation (SO2) in mild to reasonable nonproliferative diabetic retinopathy (NPDR) and in age-matched controls. Methods: One eye of each of 15 healthy topics (68 ± 6 years) and 13 topics with mild to reasonable NPDR (67 ± 10 years) was dilated. Not one of the patients with NPDR had obtained treatment for their retinopathic modifications or had any evidence of sight-threatening characteristics. Doppler Fourier-domain optical coherence tomography blood move was measured using the prototype RTVue system; six separate measurements every comprising an higher and a lower nasal pupil scan had been acquired. Six hyperspectral retinal measurements have been acquired utilizing a noninvasive hyperspectral retinal digital camera (prototype H-8.5 HR Camera). Results: Total RBF was significantly decrease in NPDR when compared to controls (42.7 ± 7.5 vs. 0.004). Mean retinal arterial and venular SO2 have been larger in NPDR than in controls (94.7 ± 2.4% vs. 0.02; 62.5 ± 5.7% vs. 0.45). The arteriovenous distinction (AV difference) was lower in the NPDR group when in comparison with controls (30.6 ± 6 vs.
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